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Using protein microarray technology to screen anti-ERCC1 monoclonal antibodies for specificity and applications in pathology
BACKGROUND: An antibody with cross-reactivity can create unexpected side effects or false diagnostic reports if used for clinical purposes. ERCC1 is being explored as a predictive diagnostic biomarker for cisplatin-based chemotherapy. High ERCC1 expression is linked to drug resistance on cisplatin-b...
Autores principales: | Ma, Donghui, Baruch, Dror, Shu, Youmin, Yuan, Kehu, Sun, Zairen, Ma, Kaiyan, Hoang, Toan, Fu, Wei, Min, Li, Lan, Zhu-Sheng, Wang, Fangxun, Mull, Lori, He, Wei-Wu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526464/ https://www.ncbi.nlm.nih.gov/pubmed/23171216 http://dx.doi.org/10.1186/1472-6750-12-88 |
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