Low-dose plasmid DNA treatment increases plasma vasopressin and regulates blood pressure in experimental endotoxemia

BACKGROUND: Although plasmid DNA encoding an antigen from pathogens or tumor cells has been widely studied as vaccine, the use of plasmid vector (without insert) as therapeutic agent requires further investigation. RESULTS: Here, we showed that plasmid DNA (pcDNA3) at low doses inhibits the producti...

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Detalles Bibliográficos
Autores principales: Malardo, Thiago, Batalhão, Marcelo E, Panunto-Castelo, Ademilson, Almeida, Luciana P, Padilha, Everton, Fontoura, Isabela C, Silva, Célio L, Carnio, Evelin C, Coelho-Castelo, Arlete AM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526548/
https://www.ncbi.nlm.nih.gov/pubmed/23137350
http://dx.doi.org/10.1186/1471-2172-13-59

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