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mRNA:guanine-N7 cap methyltransferases: identification of novel members of the family, evolutionary analysis, homology modeling, and analysis of sequence-structure-function relationships
BACKGROUND: The 5'-terminal cap structure plays an important role in many aspects of mRNA metabolism. Capping enzymes encoded by viruses and pathogenic fungi are attractive targets for specific inhibitors. There is a large body of experimental data on viral and cellular methyltransferases (MTas...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC35267/ https://www.ncbi.nlm.nih.gov/pubmed/11472630 http://dx.doi.org/10.1186/1471-2105-2-2 |