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Postsynaptic Receptors for Amyloid-β Oligomers as Mediators of Neuronal Damage in Alzheimer’s Disease

The neurotoxic effect of amyloid-β peptide (Aβ) over the central synapses has been described and is reflected in the decrease of some postsynaptic excitatory proteins, the alteration in the number and morphology of the dendritic spines, and a decrease in long-term potentiation. Many studies has been...

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Detalles Bibliográficos
Autores principales: Dinamarca, Margarita C., Ríos, Juvenal A., Inestrosa, Nibaldo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526732/
https://www.ncbi.nlm.nih.gov/pubmed/23267328
http://dx.doi.org/10.3389/fphys.2012.00464