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Sequential deletion of genes from the African swine fever virus genome using the cre/loxP recombination system
A method has been established to sequentially delete combinations of genes from the ASFV genome to test the effect on virus replication and host responses to infection. Initially the ASFV genes MGF505 2R and MGF505 3R and a truncated MGF360 9L gene were deleted from the genome of the tissue-culture...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526793/ https://www.ncbi.nlm.nih.gov/pubmed/22902236 http://dx.doi.org/10.1016/j.virol.2012.07.021 |