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CRACM/Orai ion channel expression and function in human lung mast cells

BACKGROUND: Influx of extracellular Ca(2+) into human lung mast cells (HLMCs) is essential for the FcεRI-dependent release of preformed granule-derived mediators and newly synthesized autacoids and cytokines. However, the identity of the ion channels underlying this Ca(2+) influx is unknown. The rec...

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Detalles Bibliográficos
Autores principales:	Ashmole, Ian, Duffy, S. Mark, Leyland, Mark L., Morrison, Valerie S., Begg, Malcolm, Bradding, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mosby 2012
Materias:	Mechanisms of Allergy and Clinical Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526795/ https://www.ncbi.nlm.nih.gov/pubmed/22409987 http://dx.doi.org/10.1016/j.jaci.2012.01.070

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