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Transcriptome-wide Analysis of Exosome Targets

The exosome plays major roles in RNA processing and surveillance but the in vivo target range and substrate acquisition mechanisms remain unclear. Here we apply in vivo RNA crosslinking (CRAC) to the nucleases (Rrp44, Rrp6), two structural subunits (Rrp41, Csl4) and a cofactor (Trf4) of the yeast ex...

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Detalles Bibliográficos
Autores principales: Schneider, Claudia, Kudla, Grzegorz, Wlotzka, Wiebke, Tuck, Alex, Tollervey, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526797/
https://www.ncbi.nlm.nih.gov/pubmed/23000172
http://dx.doi.org/10.1016/j.molcel.2012.08.013