Cargando…

Transcriptome-wide Analysis of Exosome Targets

The exosome plays major roles in RNA processing and surveillance but the in vivo target range and substrate acquisition mechanisms remain unclear. Here we apply in vivo RNA crosslinking (CRAC) to the nucleases (Rrp44, Rrp6), two structural subunits (Rrp41, Csl4) and a cofactor (Trf4) of the yeast ex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schneider, Claudia, Kudla, Grzegorz, Wlotzka, Wiebke, Tuck, Alex, Tollervey, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526797/ https://www.ncbi.nlm.nih.gov/pubmed/23000172 http://dx.doi.org/10.1016/j.molcel.2012.08.013

Ejemplares similares

The nuclear RNA polymerase II surveillance system targets polymerase III transcripts
por: Wlotzka, Wiebke, et al.
Publicado: (2011)

Transcriptome-wide analysis of alternative routes for RNA substrates into the exosome complex
por: Delan-Forino, Clémentine, et al.
Publicado: (2017)

Integrity of SRP RNA is ensured by La and the nuclear RNA quality control machinery
por: Leung, Eileen, et al.
Publicado: (2014)

A Transcriptome-wide Atlas of RNP Composition Reveals Diverse Classes of mRNAs and lncRNAs
por: Tuck, Alex Charles, et al.
Publicado: (2013)

Threading the barrel of the RNA exosome
por: Schneider, Claudia, et al.
Publicado: (2013)

RNA substrate length as an indicator of exosome interactions in vivo
por: Delan-Forino, Clémentine, et al.
Publicado: (2017)

The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome
por: Schneider, Claudia, et al.
Publicado: (2009)

Strand‐specific, high‐resolution mapping of modified RNA polymerase II
por: Milligan, Laura, et al.
Publicado: (2016)

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding
por: Helwak, Aleksandra, et al.
Publicado: (2013)

Hyb: A bioinformatics pipeline for the analysis of CLASH (crosslinking, ligation and sequencing of hybrids) data()
por: Travis, Anthony J., et al.
Publicado: (2014)

RNA surveillance and the exosome
por: Tollervey, David
Publicado: (2015)

The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans
por: Wells, Graeme R., et al.
Publicado: (2016)

The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans
por: Wells, Graeme R., et al.
Publicado: (2016)

Loss of the Yeast SR Protein Npl3 Alters Gene Expression Due to Transcription Readthrough
por: Holmes, Rebecca K., et al.
Publicado: (2015)

Nuclear RNA Decay Pathways Aid Rapid Remodeling of Gene Expression in Yeast
por: Bresson, Stefan, et al.
Publicado: (2017)

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit
por: Milligan, Laura, et al.
Publicado: (2017)

Box C/D snoRNP catalysed methylation is aided by additional pre-rRNA base-pairing
por: van Nues, Robert Willem, et al.
Publicado: (2011)

Genome-Wide Distribution of RNA-DNA Hybrids Identifies RNase H Targets in tRNA Genes, Retrotransposons and Mitochondria
por: El Hage, Aziz, et al.
Publicado: (2014)

Role of Tumor Necrosis Factor-α in the Human Systemic Endotoxin-Induced Transcriptome
por: Scicluna, Brendon P., et al.
Publicado: (2013)

Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies
por: Stuendl, Anne, et al.
Publicado: (2016)

Characterization and Transcriptome Analysis of Exosomal and Nonexosomal RNAs in Bovine Adipocytes
por: Yue, Binglin, et al.
Publicado: (2020)

Transcriptome analysis of cervical cancer exosomes and detection of HPVE6*I transcripts in exosomal RNA
por: Bhat, Anjali, et al.
Publicado: (2022)

Nanostructural and Transcriptomic Analyses of Human Saliva Derived Exosomes
por: Palanisamy, Viswanathan, et al.
Publicado: (2010)

An Endoribonuclease Functionally Linked to Perinuclear mRNP Quality Control Associates with the Nuclear Pore Complexes
por: Skružný, Michal, et al.
Publicado: (2009)

Transcriptome-Wide Off-Target Effects of Steric-Blocking Oligonucleotides
por: Holgersen, Erle M., et al.
Publicado: (2021)

Mapping targets for small nucleolar RNAs in yeast
por: Dudnakova, Tatiana, et al.
Publicado: (2018)

Transcriptome reprogramming by cancer exosomes: identification of novel molecular targets in matrix and immune modulation
por: Qadir, Fatima, et al.
Publicado: (2018)

The RNA-Binding Landscape of HAX1 Protein Indicates Its Involvement in Translation and Ribosome Assembly
por: Balcerak, Anna, et al.
Publicado: (2022)

Lighting up protein design
por: Kudla, Grzegorz, et al.
Publicado: (2022)

Revelation of mRNAs and proteins in porcine milk exosomes by transcriptomic and proteomic analysis
por: Chen, Ting, et al.
Publicado: (2017)

Thiol-linked alkylation of RNA to assess expression dynamics
por: Herzog, Veronika A., et al.
Publicado: (2017)

Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery
por: Antimisiaris, Sophia G., et al.
Publicado: (2018)

Biodistribution of Exosomes and Engineering Strategies for Targeted Delivery of Therapeutic Exosomes
por: Choi, Hojun, et al.
Publicado: (2021)

Transcriptome-wide analysis of pseudouridylation in Drosophila melanogaster
por: Song, Wan, et al.
Publicado: (2022)

Effects of different rootstocks on phenolics in the skin of ‘Cabernet Sauvignon’ and widely targeted metabolome and transcriptome analysis
por: Zhang, Zhijun, et al.
Publicado: (2022)

Comparative Transcriptome and Widely Targeted Metabolome Analysis Reveals the Molecular Mechanism of Powdery Mildew Resistance in Tomato
por: Liu, Wenjuan, et al.
Publicado: (2023)

Small RNA interactome of pathogenic E. coli revealed through crosslinking of RNase E
por: Waters, Shafagh A, et al.
Publicado: (2016)

Sequencing-Based Transcriptome-Wide Targeted Genotyping for Evolutionary and Ecological Studies
por: Zhu, Xuan, et al.
Publicado: (2019)

Genome-Wide Transcriptome Analysis of Cadmium Stress in Rice
por: Oono, Youko, et al.
Publicado: (2016)

Stem cell-derived exosomal transcriptomes for wound healing
por: Chen, Guiling, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_98vbjq192ljrri5ekfsm20634k