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Choroidal melanoma with massive extraocular extensions through sclera

We report a case of choroidal melanoma with massive extraocular extensions through the sclera. A 64-year-old woman reported blurred vision in her right eye. At the first visit, visual acuity was 10/20 OD. An ophthalmological examination revealed a raised choroidal mass and exudative retinal detachme...

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Autores principales: Kimura, Motoki, Ogata, Nahoko, Shima, Chieko, Takahashi, Kanji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526915/
https://www.ncbi.nlm.nih.gov/pubmed/23271890
http://dx.doi.org/10.2147/OPTH.S38515
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author Kimura, Motoki
Ogata, Nahoko
Shima, Chieko
Takahashi, Kanji
author_facet Kimura, Motoki
Ogata, Nahoko
Shima, Chieko
Takahashi, Kanji
author_sort Kimura, Motoki
collection PubMed
description We report a case of choroidal melanoma with massive extraocular extensions through the sclera. A 64-year-old woman reported blurred vision in her right eye. At the first visit, visual acuity was 10/20 OD. An ophthalmological examination revealed a raised choroidal mass and exudative retinal detachment in the lower retina. A diagnosis of peripheral choroidal melanoma was confirmed by additional test results. Because the tumor size was large and no systemic metastasis was found, we recommended enucleation. However, the patient refused and requested only to be followed without treatment. Seven months later, the tumor showed extraocular extensions through the sclera into subconjunctival space and she finally agreed to undergo enucleation. Histopathologic findings showed that the tumor was a mixed cell malignant melanoma of the choroid. The eye was filled with tumor cells, and the tumor had massive extraocular extensions into the orbit through the sclera and scleral emissarium vessels. The intraocular tumor was markedly necrotic, which indicated rapid growth. Choroidal melanomas can increase quickly in size resulting in extraocular extensions through the sclera.
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spelling pubmed-35269152012-12-27 Choroidal melanoma with massive extraocular extensions through sclera Kimura, Motoki Ogata, Nahoko Shima, Chieko Takahashi, Kanji Clin Ophthalmol Case Report We report a case of choroidal melanoma with massive extraocular extensions through the sclera. A 64-year-old woman reported blurred vision in her right eye. At the first visit, visual acuity was 10/20 OD. An ophthalmological examination revealed a raised choroidal mass and exudative retinal detachment in the lower retina. A diagnosis of peripheral choroidal melanoma was confirmed by additional test results. Because the tumor size was large and no systemic metastasis was found, we recommended enucleation. However, the patient refused and requested only to be followed without treatment. Seven months later, the tumor showed extraocular extensions through the sclera into subconjunctival space and she finally agreed to undergo enucleation. Histopathologic findings showed that the tumor was a mixed cell malignant melanoma of the choroid. The eye was filled with tumor cells, and the tumor had massive extraocular extensions into the orbit through the sclera and scleral emissarium vessels. The intraocular tumor was markedly necrotic, which indicated rapid growth. Choroidal melanomas can increase quickly in size resulting in extraocular extensions through the sclera. Dove Medical Press 2012 2012-12-13 /pmc/articles/PMC3526915/ /pubmed/23271890 http://dx.doi.org/10.2147/OPTH.S38515 Text en © 2012 Kimura et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Case Report
Kimura, Motoki
Ogata, Nahoko
Shima, Chieko
Takahashi, Kanji
Choroidal melanoma with massive extraocular extensions through sclera
title Choroidal melanoma with massive extraocular extensions through sclera
title_full Choroidal melanoma with massive extraocular extensions through sclera
title_fullStr Choroidal melanoma with massive extraocular extensions through sclera
title_full_unstemmed Choroidal melanoma with massive extraocular extensions through sclera
title_short Choroidal melanoma with massive extraocular extensions through sclera
title_sort choroidal melanoma with massive extraocular extensions through sclera
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526915/
https://www.ncbi.nlm.nih.gov/pubmed/23271890
http://dx.doi.org/10.2147/OPTH.S38515
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