Chemical chaperones assist intracellular folding to buffer mutational variations

Hidden genetic variations harbor potential for the evolution of new traits. Molecular chaperones, that assist protein folding, may conceal genetic variations in protein coding regions. Here, we investigate if the chemical milieu of cells has the potential to alleviate intracellular protein folding;...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Anannya, Saxena, Kanika, Kasturia, Neha, Dalal, Vijit, Bhatt, Niraj, Rajkumar, Asher, Maity, Shuvadeep, Sengupta, Shantanu, Chakraborty, Kausik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527004/
https://www.ncbi.nlm.nih.gov/pubmed/22246401
http://dx.doi.org/10.1038/nchembio.768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527004/
https://www.ncbi.nlm.nih.gov/pubmed/22246401
http://dx.doi.org/10.1038/nchembio.768

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