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Cilia, calcium and the basis of left-right asymmetry
The clockwise rotation of cilia in the developing mammalian embryo drives a leftward flow of liquid; this genetically regulated biophysical force specifies left-right asymmetry of the mammalian body. How leftward flow is interpreted and information propagated to other tissues is the subject of debat...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527145/ https://www.ncbi.nlm.nih.gov/pubmed/23256866 http://dx.doi.org/10.1186/1741-7007-10-102 |
| _version_ | 1782253660561997824 |
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| author | Norris, Dominic P |
| author_facet | Norris, Dominic P |
| author_sort | Norris, Dominic P |
| collection | PubMed |
| description | The clockwise rotation of cilia in the developing mammalian embryo drives a leftward flow of liquid; this genetically regulated biophysical force specifies left-right asymmetry of the mammalian body. How leftward flow is interpreted and information propagated to other tissues is the subject of debate. Four recent papers have shed fresh light on the possible mechanisms. |
| format | Online Article Text |
| id | pubmed-3527145 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-35271452012-12-21 Cilia, calcium and the basis of left-right asymmetry Norris, Dominic P BMC Biol Opinion The clockwise rotation of cilia in the developing mammalian embryo drives a leftward flow of liquid; this genetically regulated biophysical force specifies left-right asymmetry of the mammalian body. How leftward flow is interpreted and information propagated to other tissues is the subject of debate. Four recent papers have shed fresh light on the possible mechanisms. BioMed Central 2012-12-19 /pmc/articles/PMC3527145/ /pubmed/23256866 http://dx.doi.org/10.1186/1741-7007-10-102 Text en Copyright ©2012 Norris; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Opinion Norris, Dominic P Cilia, calcium and the basis of left-right asymmetry |
| title | Cilia, calcium and the basis of left-right asymmetry |
| title_full | Cilia, calcium and the basis of left-right asymmetry |
| title_fullStr | Cilia, calcium and the basis of left-right asymmetry |
| title_full_unstemmed | Cilia, calcium and the basis of left-right asymmetry |
| title_short | Cilia, calcium and the basis of left-right asymmetry |
| title_sort | cilia, calcium and the basis of left-right asymmetry |
| topic | Opinion |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527145/ https://www.ncbi.nlm.nih.gov/pubmed/23256866 http://dx.doi.org/10.1186/1741-7007-10-102 |
| work_keys_str_mv | AT norrisdominicp ciliacalciumandthebasisofleftrightasymmetry |