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Endothelial cell senescence is associated with disrupted cell-cell junctions and increased monolayer permeability
BACKGROUND: Cellular senescence is associated with cellular dysfunction and has been shown to occur in vivo in age-related cardiovascular diseases such as atherosclerosis. Atherogenesis is accompanied by intimal accumulation of LDL and increased extravasation of monocytes towards accumulated and oxi...
Autores principales: | Krouwer, Vincent J D, Hekking, Liesbeth H P, Langelaar-Makkinje, Miriam, Regan-Klapisz, Elsa, Post, Jan Andries |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527188/ https://www.ncbi.nlm.nih.gov/pubmed/22929066 http://dx.doi.org/10.1186/2045-824X-4-12 |
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