Cargando…

Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin

BACKGROUND: Optimizing the safety and efficacy of standard chemotherapeutic agents such as cisplatin (CDDP) is of clinical relevance. Serum starvation in vitro and short-term food starvation in vivo both stress cells by the sudden depletion of paracrine growth stimulation. METHODS: The effects of se...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Yandong, Felley-Bosco, Emanuela, Marti, Thomas M, Orlowski, Katrin, Pruschy, Martin, Stahel, Rolf A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527202/ https://www.ncbi.nlm.nih.gov/pubmed/23211021 http://dx.doi.org/10.1186/1471-2407-12-571

Ejemplares similares

Differential Effects of Lovastatin on Cisplatin Responses in Normal Human Mesothelial Cells versus Cancer Cells: Implication for Therapy
por: Shi, Yandong, et al.
Publicado: (2012)

Human agonistic TRAIL receptor antibodies Mapatumumab and Lexatumumab induce apoptosis in malignant mesothelioma and act synergistically with cisplatin
por: Belyanskaya, Larisa L, et al.
Publicado: (2007)

ATM/CHK/p53 Pathway Dependent Chemopreventive and Therapeutic Activity on Lung Cancer by Pterostilbene
por: Lee, Hani, et al.
Publicado: (2016)

SALL4 induces radioresistance in nasopharyngeal carcinoma via the ATM/Chk2/p53 pathway
por: Nie, Xin, et al.
Publicado: (2019)

Trial Watch: Targeting ATM–CHK2 and ATR–CHK1 pathways for anticancer therapy
por: Manic, Gwenola, et al.
Publicado: (2015)

Phosphoproteomics reveals that cinobufotalin promotes intrahepatic cholangiocarcinoma cell apoptosis by activating the ATM/CHK2/p53 signaling pathway
por: Xia, Zhili, et al.
Publicado: (2022)

The Rad53(CHK1/CHK2)-Spt21(NPAT) and Tel1(ATM) axes couple glucose tolerance to histone dosage and subtelomeric silencing
por: Bruhn, Christopher, et al.
Publicado: (2020)

An ATM–Chk2–INCENP pathway activates the abscission checkpoint
por: Petsalaki, Eleni, et al.
Publicado: (2020)

Hedgehog Signaling in Mesothelioma: 2019 Status
por: Felley-Bosco, Emanuela
Publicado: (2019)

The Role of Wild-Type p53 in Cisplatin-Induced Chk2 Phosphorylation and the Inhibition of Platinum Resistance with a Chk2 Inhibitor
por: Liang, Xiaobing, et al.
Publicado: (2011)

Mutant IDH1 Enhances Temozolomide Sensitivity via Regulation of the ATM/CHK2 Pathway in Glioma
por: Lin, Lin, et al.
Publicado: (2021)

The predictive value of molecular markers (p53, EGFR, ATM, CHK2) in multimodally treated squamous cell carcinoma of the oesophagus
por: Sarbia, M, et al.
Publicado: (2007)

Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression
por: Di Benedetto, Anna, et al.
Publicado: (2017)

7-Ketocholesterol induces ATM/ATR, Chk1/Chk2, PI3K/Akt signalings, cytotoxicity and IL-8 production in endothelial cells
por: Chang, Mei-Chi, et al.
Publicado: (2016)

Tumour growth environment modulates Chk1 signalling pathways and Chk1 inhibitor sensitivity
por: Massey, Andrew J.
Publicado: (2016)

Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression
por: Oehl, Kathrin, et al.
Publicado: (2018)

Hedgehog Signaling in Malignant Pleural Mesothelioma
por: Felley-Bosco, Emanuela, et al.
Publicado: (2015)

The Combination of ATM and Chk1 Inhibitors Induces Synthetic Lethality in Colorectal Cancer Cells
por: Tozaki, Yuri, et al.
Publicado: (2023)

Anti-Tumorigenic Activity of Chrysin from Oroxylum indicum via Non-Genotoxic p53 Activation through the ATM-Chk2 Pathway
por: Nagasaka, Mai, et al.
Publicado: (2018)

Expression of the Long Noncoding RNA DINO in Human Papillomavirus-Positive Cervical Cancer Cells Reactivates the Dormant TP53 Tumor Suppressor through ATM/CHK2 Signaling
por: Sharma, Surendra, et al.
Publicado: (2020)

GAS5 long non-coding RNA in malignant pleural mesothelioma
por: Renganathan, Arun, et al.
Publicado: (2014)

XRRA1 Targets ATM/CHK1/2-Mediated DNA Repair in Colorectal Cancer
por: Wang, Wenjun, et al.
Publicado: (2017)

Licochalcone A Suppresses the Proliferation of Osteosarcoma Cells through Autophagy and ATM-Chk2 Activation
por: Shen, Tai-Shan, et al.
Publicado: (2019)

Sensitivity of cells to ATR and CHK1 inhibitors requires hyperactivation of CDK2 rather than endogenous replication stress or ATM dysfunction
por: Ditano, Jennifer P., et al.
Publicado: (2021)

Special Issue on Mechanisms of Mesothelioma Heterogeneity: Highlights and Open Questions
por: Felley-Bosco, Emanuela
Publicado: (2018)

Exploring the Expression of the «Dark Matter» of the Genome in Mesothelioma for Potentially Predictive Biomarkers for Prognosis and Immunotherapy
por: Felley-Bosco, Emanuela
Publicado: (2023)

Sodium fluoride causes hepatocellular S-phase arrest by activating ATM-p53-p21 and ATR-Chk1-Cdc25A pathways in mice
por: Liu, Huan, et al.
Publicado: (2017)

Inhibition of autophagy sensitizes malignant pleural mesothelioma cells to dual PI3K/mTOR inhibitors
por: Echeverry, N, et al.
Publicado: (2015)

Expression of the Stem Cell Factor Nestin in Malignant Pleural Mesothelioma Is Associated with Poor Prognosis
por: Thies, Svenja, et al.
Publicado: (2015)

ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1
por: Zhang, Peijing, et al.
Publicado: (2014)

Corrigendum to “XRRA1 Targets ATM/CHK1/2-Mediated DNA Repair in Colorectal Cancer”
por: Wang, Wenjun, et al.
Publicado: (2021)

Identification of a seven glycopeptide signature for malignant pleural mesothelioma in human serum by selected reaction monitoring
por: Cerciello, Ferdinando, et al.
Publicado: (2013)

Mangrove dolabrane‐type of diterpenes tagalsins suppresses tumor growth via ROS‐mediated apoptosis and ATM/ATR–Chk1/Chk2‐regulated cell cycle arrest
por: Neumann, Jennifer, et al.
Publicado: (2015)

Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells
por: Sahu, R P, et al.
Publicado: (2009)

Clinicopathological Significance of ATM-Chk2 Expression in Sporadic Breast Cancers: a Comprehensive Analysis in Large Cohorts()
por: Abdel-Fatah, Tarek M.A., et al.
Publicado: (2014)

Cyclin D1 Binding Protein 1 Responds to DNA Damage through the ATM–CHK2 Pathway
por: Niwa, Yusuke, et al.
Publicado: (2022)

An ATM/Chk2-mediated DNA damage responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells
por: Nikitin, Pavel A., et al.
Publicado: (2010)

An ATM/Chk2-mediated DNA damage responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells
por: Nikitin, Pavel, et al.
Publicado: (2010)

Inhibition of MELK produces potential anti‐tumour effects in bladder cancer by inducing G1/S cell cycle arrest via the ATM/CHK2/p53 pathway
por: Chen, Song, et al.
Publicado: (2019)

Non-Coding Transcript Heterogeneity in Mesothelioma: Insights from Asbestos-Exposed Mice
por: Felley-Bosco, Emanuela, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_a7ljvjuablic88iggvamtj8m3o