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Parameter Identifiability and Sensitivity Analysis Predict Targets for Enhancement of STAT1 Activity in Pancreatic Cancer and Stellate Cells

The present work exemplifies how parameter identifiability analysis can be used to gain insights into differences in experimental systems and how uncertainty in parameter estimates can be handled. The case study, presented here, investigates interferon-gamma (IFNγ) induced STAT1 signalling in two ce...

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Detalles Bibliográficos
Autores principales:	Rateitschak, Katja, Winter, Felix, Lange, Falko, Jaster, Robert, Wolkenhauer, Olaf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527226/ https://www.ncbi.nlm.nih.gov/pubmed/23284277 http://dx.doi.org/10.1371/journal.pcbi.1002815

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