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DNA Topoisomerases Maintain Promoters in a State Competent for Transcriptional Activation in Saccharomyces cerevisiae
To investigate the role of DNA topoisomerases in transcription, we have studied global gene expression in Saccharomyces cerevisiae cells deficient for topoisomerases I and II and performed single-gene analyses to support our findings. The genome-wide studies show a general transcriptional down-regul...
Autores principales: | Pedersen, Jakob Madsen, Fredsoe, Jacob, Roedgaard, Morten, Andreasen, Lotte, Mundbjerg, Kamilla, Kruhøffer, Mogens, Brinch, Marie, Schierup, Mikkel Heide, Bjergbaek, Lotte, Andersen, Anni Hangaard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527272/ https://www.ncbi.nlm.nih.gov/pubmed/23284296 http://dx.doi.org/10.1371/journal.pgen.1003128 |
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