Insertion/Deletion Polymorphisms in the ΔNp63 Promoter Are a Risk Factor for Bladder Exstrophy Epispadias Complex

Bladder exstrophy epispadias complex (BEEC) is a severe congenital anomaly; however, the genetic and molecular mechanisms underlying the formation of BEEC remain unclear. TP63, a member of TP53 tumor suppressor gene family, is expressed in bladder urothelium and skin over the external genitalia duri...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilkins, Simon, Zhang, Ke Wei, Mahfuz, Istiak, Quantin, Renaud, D'Cruz, Nancy, Hutson, John, Ee, Michael, Bagli, Darius, Aitken, Karen, Fong, Fion Nga-Yin, Ng, Patrick Kwok-Shing, Tsui, Stephen Kwok-Wing, Fung, Wendy Yin-Wan, Banu, Tahmina, Thakre, Atul, Johar, Kaid, Jaureguizar, Enrique, Li, Long, Cheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527294/
https://www.ncbi.nlm.nih.gov/pubmed/23284286
http://dx.doi.org/10.1371/journal.pgen.1003070

Ejemplares similares

Ejemplares similares