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ATX1-Generated H3K4me3 Is Required for Efficient Elongation of Transcription, Not Initiation, at ATX1-Regulated Genes

Tri-methylated H3 lysine 4 (H3K4me3) is associated with transcriptionally active genes, but its function in the transcription process is still unclear. Point mutations in the catalytic domain of ATX1 (ARABIDOPSIS TRITHORAX1), a H3K4 methyltransferase, and RNAi knockdowns of subunits of the AtCOMPASS...

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Detalles Bibliográficos
Autores principales: Ding, Yong, Ndamukong, Ivan, Xu, Zaoshi, Lapko, Hanna, Fromm, Michael, Avramova, Zoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527332/
https://www.ncbi.nlm.nih.gov/pubmed/23284292
http://dx.doi.org/10.1371/journal.pgen.1003111

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