Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice

BACKGROUND: Telmisartan is a well-established angiotensin II type 1 receptor blocker that improves insulin sensitivity in animal models of obesity and insulin resistance, as well as in humans. Telmisartan has been reported to function as a partial agonist of the peroxisome proliferator-activated rec...

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Detalles Bibliográficos
Autores principales: Shiota, Asuka, Shimabukuro, Michio, Fukuda, Daiju, Soeki, Takeshi, Sato, Hiromi, Uematsu, Etsuko, Hirata, Yoichiro, Kurobe, Hirotsugu, Maeda, Norikazu, Sakaue, Hiroshi, Masuzaki, Hiroaki, Shimomura, Iichiro, Sata, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527353/
https://www.ncbi.nlm.nih.gov/pubmed/23137106
http://dx.doi.org/10.1186/1475-2840-11-139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527353/
https://www.ncbi.nlm.nih.gov/pubmed/23137106
http://dx.doi.org/10.1186/1475-2840-11-139

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