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Methylphenidate Enhances NMDA-Receptor Response in Medial Prefrontal Cortex via Sigma-1 Receptor: A Novel Mechanism for Methylphenidate Action
Methylphenidate (MPH), commercially called Ritalin or Concerta, has been widely used as a drug for Attention Deficit Hyperactivity Disorder (ADHD). Noteworthily, growing numbers of young people using prescribed MPH improperly for pleasurable enhancement, take high risk of addiction. Thus, understand...
Autores principales: | Zhang, Chun-Lei, Feng, Ze-Jun, Liu, Yue, Ji, Xiao-Hua, Peng, Ji-Yun, Zhang, Xue-Han, Zhen, Xue-Chu, Li, Bao-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527396/ https://www.ncbi.nlm.nih.gov/pubmed/23284812 http://dx.doi.org/10.1371/journal.pone.0051910 |
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