Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-Like Skin Inflammatory Responses in Adult Mice

BACKGROUND: Ctip2 is crucial for epidermal homeostasis and protective barrier formation in developing mouse embryos. Selective ablation of Ctip2 in epidermis leads to increased transepidermal water loss (TEWL), impaired epidermal proliferation, terminal differentiation, as well as altered lipid comp...

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Detalles Bibliográficos
Autores principales: Wang, Zhixing, Zhang, Ling-juan, Guha, Gunjan, Li, Shan, Kyrylkova, Kateryna, Kioussi, Chrissa, Leid, Mark, Ganguli-Indra, Gitali, Indra, Arup K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527437/
https://www.ncbi.nlm.nih.gov/pubmed/23284675
http://dx.doi.org/10.1371/journal.pone.0051262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527437/
https://www.ncbi.nlm.nih.gov/pubmed/23284675
http://dx.doi.org/10.1371/journal.pone.0051262

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