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Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-Like Skin Inflammatory Responses in Adult Mice
BACKGROUND: Ctip2 is crucial for epidermal homeostasis and protective barrier formation in developing mouse embryos. Selective ablation of Ctip2 in epidermis leads to increased transepidermal water loss (TEWL), impaired epidermal proliferation, terminal differentiation, as well as altered lipid comp...
Autores principales: | Wang, Zhixing, Zhang, Ling-juan, Guha, Gunjan, Li, Shan, Kyrylkova, Kateryna, Kioussi, Chrissa, Leid, Mark, Ganguli-Indra, Gitali, Indra, Arup K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527437/ https://www.ncbi.nlm.nih.gov/pubmed/23284675 http://dx.doi.org/10.1371/journal.pone.0051262 |
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