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The Caenorhabditis elegans THO Complex Is Required for the Mitotic Cell Cycle and Development

THO is a conserved eukaryotic complex involved in mRNP biogenesis and RNA export that plays an important role in preventing transcription- and RNA-mediated genome instability in mitosis and meiosis. In mammals THO is essential for embryogenesis, which limits our capacity to analyze the physiological...

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Detalles Bibliográficos
Autores principales: Castellano-Pozo, Maikel, García-Muse, Tatiana, Aguilera, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527488/
https://www.ncbi.nlm.nih.gov/pubmed/23285047
http://dx.doi.org/10.1371/journal.pone.0052447