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The Caenorhabditis elegans THO Complex Is Required for the Mitotic Cell Cycle and Development
THO is a conserved eukaryotic complex involved in mRNP biogenesis and RNA export that plays an important role in preventing transcription- and RNA-mediated genome instability in mitosis and meiosis. In mammals THO is essential for embryogenesis, which limits our capacity to analyze the physiological...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527488/ https://www.ncbi.nlm.nih.gov/pubmed/23285047 http://dx.doi.org/10.1371/journal.pone.0052447 |