Cargando…
How Difficult Is It to Fold a Knotted Protein? In Silico Insights from Surface-Tethered Folding Experiments
We explore the effect of surface tethering on the folding process of a lattice protein that contains a trefoil knot in its native structure via Monte Carlo simulations. We show that the outcome of the tethering experiment depends critically on which terminus is used to link the protein to a chemical...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527535/ https://www.ncbi.nlm.nih.gov/pubmed/23284997 http://dx.doi.org/10.1371/journal.pone.0052343 |