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Anti-Chlamydial Th17 Responses Are Controlled by the Inducible Costimulator Partially through Phosphoinositide 3-Kinase Signaling

We previously showed that mice deficient in the Inducible Costimulator ligand (ICOSL-KO) develop more severe disease and lung pathology with delayed bacterial clearance upon respiratory infection of Chlamydia muridarum. Importantly, the exacerbation of disease in ICOSL-KO mice was seen despite heigh...

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Detalles Bibliográficos
Autores principales: Gao, Xiaoling, Gigoux, Mathieu, Yang, Jie, Leconte, Julien, Yang, Xi, Suh, Woong-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527575/
https://www.ncbi.nlm.nih.gov/pubmed/23285133
http://dx.doi.org/10.1371/journal.pone.0052657