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Negative Regulation of Pulmonary Th17 Responses by C3a Anaphylatoxin during Allergic Inflammation in Mice

Activation of complement is one of the earliest immune responses to exogenous threats, resulting in various cleavage products including anaphylatoxin C3a. In addition to its contribution to host defense, C3a has been shown to mediate Th2 responses in animal models of asthma. However, the role of C3a...

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Detalles Bibliográficos
Autores principales: Lim, Hoyong, Kim, Young Uk, Drouin, Scott M., Mueller-Ortiz, Stacey, Yun, Kyoungah, Morschl, Eva, Wetsel, Rick A., Chung, Yeonseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527591/
https://www.ncbi.nlm.nih.gov/pubmed/23285141
http://dx.doi.org/10.1371/journal.pone.0052666