Stat3 Is Required to Maintain the Full Differentiation Potential of Mammary Stem Cells and the Proliferative Potential of Mammary Luminal Progenitors

Stat3 has a defined role in mammary gland where it is a critical mediator of cell death during post-lactational regression. On the other hand, Stat3 is required for the self-renewal of embryonic stem cells and is sufficient for the induction of a naïve pluripotent state in epiblast stem cells. Mamma...

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Detalles Bibliográficos
Autores principales: Staniszewska, Anna D., Pensa, Sara, Caffarel, Maria M., Anderson, Lisa H., Poli, Valeria, Watson, Christine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527594/
https://www.ncbi.nlm.nih.gov/pubmed/23285109
http://dx.doi.org/10.1371/journal.pone.0052608

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