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Macrophage Metalloelastase (MMP-12) Deficiency Mitigates Retinal Inflammation and Pathological Angiogenesis in Ischemic Retinopathy

Pathological angiogenesis is a major cause of vision loss in ischemic and inflammatory retinal diseases. Recent evidence implicates macrophage metalloelastase (MMP-12), a macrophage-derived elastinolytic protease in inflammation, tissue remodeling and angiogenesis. However, little is known about the...

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Detalles Bibliográficos
Autores principales:	Li, Jingming, Wang, Joshua J., Peng, Qisheng, Chen, Chen, Humphrey, Mary Beth, Heinecke, Jay, Zhang, Sarah X.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527600/ https://www.ncbi.nlm.nih.gov/pubmed/23285156 http://dx.doi.org/10.1371/journal.pone.0052699

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