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How scaffolds shape MAPK signaling: what we know and opportunities for systems approaches

Scaffolding proteins add a new layer of complexity to the dynamics of cell signaling. Above their basic function to bring several components of a signaling pathway together, recent experimental research has found that scaffolds influence signaling in a much more complex way: scaffolds can exert some...

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Detalles Bibliográficos
Autores principales: Witzel, Franziska, Maddison, Louise, Blüthgen, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527831/
https://www.ncbi.nlm.nih.gov/pubmed/23267331
http://dx.doi.org/10.3389/fphys.2012.00475