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Electrostatic Ratchet in the Protective Antigen Channel Promotes Anthrax Toxin Translocation
Central to the power-stroke and Brownian-ratchet mechanisms of protein translocation is the process through which nonequilibrium fluctuations are rectified or ratcheted by the molecular motor to transport substrate proteins along a specific axis. We investigated the ratchet mechanism using anthrax t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527960/ https://www.ncbi.nlm.nih.gov/pubmed/23115233 http://dx.doi.org/10.1074/jbc.M112.419598 |