Cargando…

Cysteine 70 of Ankyrin-G Is S-Palmitoylated and Is Required for Function of Ankyrin-G in Membrane Domain Assembly

Ankyrin-G (AnkG) coordinates protein composition of diverse membrane domains, including epithelial lateral membranes and neuronal axon initial segments. However, how AnkG itself localizes to these membrane domains is not understood. We report that AnkG remains on the plasma membrane in Madin-Darby c...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Meng, Jenkins, Paul, Bennett, Vann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2012
Materias:	Membrane Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527982/ https://www.ncbi.nlm.nih.gov/pubmed/23129772 http://dx.doi.org/10.1074/jbc.M112.417501

Ejemplares similares

A Single Divergent Exon Inhibits Ankyrin-B Association with the Plasma Membrane
por: He, Meng, et al.
Publicado: (2013)

Ankyrin-G palmitoylation and βII-spectrin binding to phosphoinositide lipids drive lateral membrane assembly
por: He, Meng, et al.
Publicado: (2014)

Restriction of 480/270-kD Ankyrin (G) to Axon Proximal Segments Requires Multiple Ankyrin (G)-specific Domains
por: Zhang, Xu, et al.
Publicado: (1998)

Dynamic spectrin/ankyrin-G microdomains promote lateral membrane assembly by opposing endocytosis
por: Jenkins, Paul M., et al.
Publicado: (2015)

Identification of a Novel Sequence Motif Recognized by the Ankyrin Repeat Domain of zDHHC17/13 S-Acyltransferases
por: Lemonidis, Kimon, et al.
Publicado: (2015)

Structural basis for the membrane association of ankyrinG via palmitoylation
por: Fujiwara, Yuichiro, et al.
Publicado: (2016)

Neurodevelopmental mutation of giant ankyrin-G disrupts a core mechanism for axon initial segment assembly
por: Yang, Rui, et al.
Publicado: (2019)

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments
por: Jenkins, Scott M., et al.
Publicado: (2001)

E-cadherin Polarity Is Determined by a Multifunction Motif Mediating Lateral Membrane Retention through Ankyrin-G and Apical-lateral Transcytosis through Clathrin
por: Jenkins, Paul M, et al.
Publicado: (2013)

Multiple Palmitoyltransferases Are Required for Palmitoylation-dependent Regulation of Large Conductance Calcium- and Voltage-activated Potassium Channels
por: Tian, Lijun, et al.
Publicado: (2010)

Hypoxia-inducible Factor-1α (HIF1α) Switches on Transient Receptor Potential Ankyrin Repeat 1 (TRPA1) Gene Expression via a Hypoxia Response Element-like Motif to Modulate Cytokine Release
por: Hatano, Noriyuki, et al.
Publicado: (2012)

Structural basis of diverse membrane target recognitions by ankyrins
por: Wang, Chao, et al.
Publicado: (2014)

The Ankyrin Repeat Domain Controls Presynaptic Localization of Drosophila Ankyrin2 and Is Essential for Synaptic Stability
por: Weber, Tobias, et al.
Publicado: (2019)

Ankyrin(G) Is Required for Clustering of Voltage-gated Na Channels at Axon Initial Segments and for Normal Action Potential Firing
por: Zhou, Daixing, et al.
Publicado: (1998)

GLIAL ANKYRINS FACILITATE PARANODAL AXOGLIAL JUNCTION ASSEMBLY
por: Chang, Kae-Jiun, et al.
Publicado: (2014)

Ankyrin-B Interactions with Spectrin and Dynactin-4 Are Required for Dystrophin-based Protection of Skeletal Muscle from Exercise Injury
por: Ayalon, Gai, et al.
Publicado: (2011)

Nodes of Ranvier and axon initial segments are ankyrin G–dependent domains that assemble by distinct mechanisms
por: Dzhashiashvili, Yulia, et al.
Publicado: (2007)

Palmitoylation controls the stability of 190 kDa ankyrin-G in dendritic spines and is regulated by ZDHHC8 and lithium
por: Piguel, Nicolas H., et al.
Publicado: (2023)

AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity
por: Hedstrom, Kristian L., et al.
Publicado: (2008)

Giant ankyrin-G regulates cardiac function
por: Cavus, Omer, et al.
Publicado: (2021)

Roles and mechanisms of ankyrin-G in neuropsychiatric disorders
por: Yoon, Sehyoun, et al.
Publicado: (2022)

An Electrostatic Switch Controls Palmitoylation of the Large Conductance Voltage- and Calcium-activated Potassium (BK) Channel
por: Jeffries, Owen, et al.
Publicado: (2012)

G-quadruplexes are specifically recognized and distinguished by selected designed ankyrin repeat proteins
por: Scholz, Oliver, et al.
Publicado: (2014)

Ankyrin-B Is Required for Intracellular Sorting of Structurally Diverse Ca(2+) Homeostasis Proteins
por: Tuvia, Shmuel, et al.
Publicado: (1999)

Palmitoylation of the S0-S1 Linker Regulates Cell Surface Expression of Voltage- and Calcium-activated Potassium (BK) Channels
por: Jeffries, Owen, et al.
Publicado: (2010)

Palmitoylation of the β4-Subunit Regulates Surface Expression of Large Conductance Calcium-activated Potassium Channel Splice Variants
por: Chen, Lie, et al.
Publicado: (2013)

An unfolding role for ankyrin-G at the axon initial segment
por: Salzer, James L.
Publicado: (2019)

Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions
por: Chen, Keyu, et al.
Publicado: (2017)

Ankyrin G Membrane Partners Drive the Establishment and Maintenance of the Axon Initial Segment
por: Leterrier, Christophe, et al.
Publicado: (2017)

Two Conserved Residues Are Important for Inducing Highly Ordered Membrane Domains by the Transmembrane Domain of Influenza Hemagglutinin
por: Ge, Mingtao, et al.
Publicado: (2011)

Ankyrin-G Regulates Forebrain Connectivity and Network Synchronization via Interaction with GABARAP
por: Nelson, AD, et al.
Publicado: (2018)

In Situ Determination of Structure and Fluctuations of Coexisting Fluid Membrane Domains
por: Heftberger, Peter, et al.
Publicado: (2015)

Bending Rigidities and Interdomain Forces in Membranes with Coexisting Lipid Domains
por: Kollmitzer, Benjamin, et al.
Publicado: (2015)

Ankyrin domains across the Tree of Life
por: Jernigan, Kristin K., et al.
Publicado: (2014)

Nervous System Defects of Ankyrin(B) (−/−) Mice Suggest Functional Overlap between the Cell Adhesion Molecule L1 and 440-kD Ankyrin(B )in Premyelinated Axons
por: Scotland, Paula, et al.
Publicado: (1998)

Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importance
por: Mulinta, Ras, et al.
Publicado: (2017)

GM1 Softens POPC Membranes and Induces the Formation of Micron-Sized Domains
por: Fricke, Nico, et al.
Publicado: (2016)

FSCS Reveals the Complexity of Lipid Domain Dynamics in the Plasma Membrane of Live Cells
por: Nicovich, Philip R., et al.
Publicado: (2018)

Structure Prediction of the Second Extracellular Loop in G-Protein-Coupled Receptors
por: Kmiecik, Sebastian, et al.
Publicado: (2014)

Ankyrin-B is lipid-modified by S-palmitoylation to promote dendritic membrane scaffolding of voltage-gated sodium channel Na(V)1.2 in neurons
por: Gupta, Julie P., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_92qgr2v437bit86309814vfs9e