Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, its Related Substances, and Degradation Products

A novel, stability-indicating UHPLC method was developed for the quantitative determination of Abacavir sulfate, its related substances, and forced degradation impurities in bulk drugs. The chromatographic separation was achieved on a Waters Acquity BEH C(8), 50 mm × 2.1 mm, 1.7 μm particle size col...

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Detalles Bibliográficos
Autores principales: Vukkum, Pallavi, Deshpande, Girish R., Babu, J. Moses, Muralikrishna, R., Jagu, Pavani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Österreichische Apotheker-Verlagsgesellschaft 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528060/
https://www.ncbi.nlm.nih.gov/pubmed/23264939
http://dx.doi.org/10.3797/scipharm.1206-11

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