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Biochemical and Computational Approaches to Improve the Clinical Treatment of Dopa Decarboxylase-Related Diseases: An Overview

Dopa decarboxylase (DDC) is a pyridoxal 5’-phosphate (PLP)-dependent enzyme that by catalyzing the decarboxylation of L-Dopa and L-5-hydroxytryptophan produces the neurotransmitters dopamine and serotonin. The functional properties of pig kidney and human DDC enzymes have been extensively characteri...

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Detalles Bibliográficos
Autores principales:	Cellini, Barbara, Montioli, Riccardo, Oppici, Elisa, Voltattorni, Carla Borri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Open 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528064/ https://www.ncbi.nlm.nih.gov/pubmed/23264832 http://dx.doi.org/10.2174/1874091X01206010131

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