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SIRT6 is required for maintenance of telomere position effect in human cells

In Saccharomyces cerevisiae, the repressive chromatin environment at telomeres gives rise to telomere position effect (TPE), the epigenetic silencing of telomere-proximal genes. Chromatin-modifying factors that control TPE in yeast have been extensively studied, and among these, the lifespan regulat...

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Detalles Bibliográficos
Autores principales:	Tennen, Ruth I., Bua, Dennis J., Wright, Woodring E., Chua, Katrin F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528101/ https://www.ncbi.nlm.nih.gov/pubmed/21847107 http://dx.doi.org/10.1038/ncomms1443

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