Cargando…
Induction of Apoptosis by Sinulariolide from Soft Coral through Mitochondrial-Related and p38MAPK Pathways on Human Bladder Carcinoma Cells
Sinulariolide, an isolated compound from the soft coral Sinularia flexibilis, possesses the anti-proliferative, anti-migratory and apoptosis-inducing activities against the TSGH bladder carcinoma cell. The anti-tumor effects of sinulariolide were determined by 3-(4,5-cimethylthiazol-2-yl)-2,5-diphen...
Autores principales: | Neoh, Choo-Aun, Wang, Robert Y.-L., Din, Zhong-Hao, Su, Jui-Hsin, Chen, Yu-Kuei, Tsai, Feng-Jen, Weng, Shun-Hsiang, Wu, Yu-Jen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528132/ https://www.ncbi.nlm.nih.gov/pubmed/23249971 http://dx.doi.org/10.3390/md10122893 |
Ejemplares similares
-
Sinulariolide Suppresses Human Hepatocellular Carcinoma Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 through MAPKs and PI3K/Akt Signaling Pathways
por: Wu, Yu-Jen, et al.
Publicado: (2015) -
Sinulariolide Inhibits Gastric Cancer Cell Migration and Invasion through Downregulation of the EMT Process and Suppression of FAK/PI3K/AKT/mTOR and MAPKs Signaling Pathways
por: Wu, Yu-Jen, et al.
Publicado: (2019) -
Flaccidoxide-13-Acetate Extracted from the Soft Coral Cladiella kashmani Reduces Human Bladder Cancer Cell Migration and Invasion through Reducing Activation of the FAK/PI3K/AKT/mTOR Signaling Pathway
por: Neoh, Choo-Aun, et al.
Publicado: (2017) -
11-epi-Sinulariolide Acetate Reduces Cell Migration and Invasion of Human Hepatocellular Carcinoma by Reducing the Activation of ERK1/2, p38MAPK and FAK/PI3K/AKT/mTOR Signaling Pathways
por: Lin, Jen-Jie, et al.
Publicado: (2014) -
Sinulariolide Induced Hepatocellular Carcinoma Apoptosis through Activation of Mitochondrial-Related Apoptotic and PERK/eIF2α/ATF4/CHOP Pathway
por: Chen, Yi-Jen, et al.
Publicado: (2013)