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MHC Class II and Non-MHC Class II Genes Differentially Influence Humoral Immunity to Bacillus anthracis Lethal Factor and Protective Antigen

Anthrax Lethal Toxin consists of Protective Antigen (PA) and Lethal Factor (LF), and current vaccination strategies focus on eliciting antibodies to PA. In human vaccination, the response to PA can vary greatly, and the response is often directed toward non-neutralizing epitopes. Variable vaccine re...

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Detalles Bibliográficos
Autores principales: Garman, Lori, Dumas, Eric K., Kurella, Sridevi, Hunt, Jonathan J., Crowe, Sherry R., Nguyen, Melissa L., Cox, Philip M., James, Judith A., Farris, A. Darise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528256/
https://www.ncbi.nlm.nih.gov/pubmed/23342680
http://dx.doi.org/10.3390/toxins4121451