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High diversity and no significant selection signal of human ADH1B gene in Tibet

BACKGROUND: ADH1B is one of the most studied human genes with many polymorphic sites. One of the single nucleotide polymorphism (SNP), rs1229984, coding for the Arg48His substitution, have been associated with many serious diseases including alcoholism and cancers of the digestive system. The derive...

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Detalles Bibliográficos
Autores principales: Lu, Yan, Kang, Longli, Hu, Kang, Wang, Chuanchao, Sun, Xiaoji, Chen, Feng, Kidd, Judith R, Kidd, Kenneth K, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528464/
https://www.ncbi.nlm.nih.gov/pubmed/23176670
http://dx.doi.org/10.1186/2041-2223-3-23

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