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High diversity and no significant selection signal of human ADH1B gene in Tibet
BACKGROUND: ADH1B is one of the most studied human genes with many polymorphic sites. One of the single nucleotide polymorphism (SNP), rs1229984, coding for the Arg48His substitution, have been associated with many serious diseases including alcoholism and cancers of the digestive system. The derive...
Autores principales: | Lu, Yan, Kang, Longli, Hu, Kang, Wang, Chuanchao, Sun, Xiaoji, Chen, Feng, Kidd, Judith R, Kidd, Kenneth K, Li, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528464/ https://www.ncbi.nlm.nih.gov/pubmed/23176670 http://dx.doi.org/10.1186/2041-2223-3-23 |
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