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Evidence for Vpr-dependent HIV-1 Replication in Human CD4(+) CEM.NKR T-Cells

BACKGROUND: Vpr is exclusively expressed in primate lentiviruses and contributes to viral replication and disease progression in vivo. HIV-1 Vpr has two major activities in vitro: arrest of cell cycle in the G2 phase (G2 arrest), and enhancement of viral replication in macrophages. Previously, we re...

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Detalles Bibliográficos
Autores principales:	Zhou, Tao, Dang, Ying, Baker, Jacob J, Zhou, Jiajun, Zheng, Yong-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528630/ https://www.ncbi.nlm.nih.gov/pubmed/23134572 http://dx.doi.org/10.1186/1742-4690-9-93

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