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Local treatment of a bone graft by soaking in zoledronic acid inhibits bone resorption and bone formation. A bone chamber study in rats

BACKGROUND: Bone grafts are frequently used in orthopaedic surgery. Graft remodelling is advantageous but can occur too quickly, and premature bone resorption might lead to decreased mechanical integrity of the graft. Bisphosphonates delay osteoclastic bone resorption but may also impair formation o...

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Detalles Bibliográficos
Autores principales: Belfrage, Ola, Isaksson, Hanna, Tägil, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528664/
https://www.ncbi.nlm.nih.gov/pubmed/23217097
http://dx.doi.org/10.1186/1471-2474-13-240

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