G6f-Like Is an ITAM-Containing Collagen Receptor in Thrombocytes

Collagen activates mammalian platelets through a complex of the immunoglobulin (Ig) receptor GPVI and the Fc receptor γ-chain, which has an immunoreceptor tyrosine-based activation motif (ITAM). Cross-linking of GPVI mediates activation through the sequential activation of Src and Syk family kinases...

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Detalles Bibliográficos
Autores principales: Hughes, Craig E., Radhakrishnan, Uvaraj P., Lordkipanidzé, Marie, Egginton, Stuart, Dijkstra, Johannes M., Jagadeeswaran, Pudur, Watson, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528668/
https://www.ncbi.nlm.nih.gov/pubmed/23285115
http://dx.doi.org/10.1371/journal.pone.0052622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528668/
https://www.ncbi.nlm.nih.gov/pubmed/23285115
http://dx.doi.org/10.1371/journal.pone.0052622

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