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Novel Features of a PIWI-Like Protein Homolog in the Parasitic Protozoan Leishmania

In contrast to nearly all eukaryotes, the Old World Leishmania species L. infantum and L. major lack the bona fide RNAi machinery genes. Interestingly, both Leishmania genomes code for an atypical Argonaute-like protein that possesses a PIWI domain but lacks the PAZ domain found in Argonautes from R...

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Detalles Bibliográficos
Autores principales: Padmanabhan, Prasad K., Dumas, Carole, Samant, Mukesh, Rochette, Annie, Simard, Martin J., Papadopoulou, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528672/
https://www.ncbi.nlm.nih.gov/pubmed/23285111
http://dx.doi.org/10.1371/journal.pone.0052612