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Aberrant Sporogonic Development of Dmc1 (a Meiotic Recombinase) Deficient Plasmodium berghei Parasites

BACKGROUND: In Plasmodium, meiosis occurs in diploid zygotes as they develop into haploid motile ookinetes inside the mosquito. Further sporogonic development involves transformation of ookinetes into oocysts and formation of infective sporozoites. METHODOLOGY/PRINCIPAL FINDINGS: Reverse genetics wa...

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Detalles Bibliográficos
Autores principales:	Mlambo, Godfree, Coppens, Isabelle, Kumar, Nirbhay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528682/ https://www.ncbi.nlm.nih.gov/pubmed/23285059 http://dx.doi.org/10.1371/journal.pone.0052480

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