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Cubic regression-based degree of correction predicts the performance of whole bisulfitome amplified DNA methylation analysis
Epigenetic mechanisms, including DNA methylation, are important determinants in development and disease. There is a need for technologies capable of detecting small variations in methylation levels in an accurate and reproducible manner, even if only limited amounts of DNA are available (which is th...
Autores principales: | Fernandez-Jimenez, Nora, Plaza-Izurieta, Leticia, Lopez-Euba, Tamara, Jauregi-Miguel, Amaia, Ramon Bilbao, Jose |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528690/ https://www.ncbi.nlm.nih.gov/pubmed/23154537 http://dx.doi.org/10.4161/epi.22846 |
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