In Silico Target-Specific siRNA Design Based on Domain Transfer in Heterogeneous Data

RNA interference via exogenous small interference RNAs (siRNA) is a powerful tool in gene function study and disease treatment. Designing efficient and specific siRNA on target gene remains the key issue in RNAi. Although various in silico models have been proposed for rational siRNA design, most of...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Zhou, Han, Zhang, Kui, Shi, Xiaoxiao, Fan, Wei, Zhu, Ruixin, Yu, Philip S., Cao, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528743/
https://www.ncbi.nlm.nih.gov/pubmed/23284642
http://dx.doi.org/10.1371/journal.pone.0050697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528743/
https://www.ncbi.nlm.nih.gov/pubmed/23284642
http://dx.doi.org/10.1371/journal.pone.0050697

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