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In Silico Target-Specific siRNA Design Based on Domain Transfer in Heterogeneous Data
RNA interference via exogenous small interference RNAs (siRNA) is a powerful tool in gene function study and disease treatment. Designing efficient and specific siRNA on target gene remains the key issue in RNAi. Although various in silico models have been proposed for rational siRNA design, most of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528743/ https://www.ncbi.nlm.nih.gov/pubmed/23284642 http://dx.doi.org/10.1371/journal.pone.0050697 |