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Resveratrol Prevents Ammonia Toxicity in Astroglial Cells
Ammonia is implicated as a neurotoxin in brain metabolic disorders associated with hyperammonemia. Acute ammonia toxicity can be mediated by an excitotoxic mechanism, oxidative stress and nitric oxide (NO) production. Astrocytes interact with neurons, providing metabolic support and protecting again...
Autores principales: | Bobermin, Larissa Daniele, Quincozes-Santos, André, Guerra, Maria Cristina, Leite, Marina Concli, Souza, Diogo Onofre, Gonçalves, Carlos-Alberto, Gottfried, Carmem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528750/ https://www.ncbi.nlm.nih.gov/pubmed/23284918 http://dx.doi.org/10.1371/journal.pone.0052164 |
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