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Claudin-4 Deficiency Results in Urothelial Hyperplasia and Lethal Hydronephrosis
Claudin (Cld)-4 is one of the dominant Clds expressed in the kidney and urinary tract, including selective segments of renal nephrons and the entire urothelium from the pelvis to the bladder. We generated Cldn4 (−/−) mice and found that these mice had increased mortality due to hydronephrosis of rel...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528782/ https://www.ncbi.nlm.nih.gov/pubmed/23284964 http://dx.doi.org/10.1371/journal.pone.0052272 |