FMR1 targets distinct mRNA sequence elements to regulate protein expression

Fragile-X Syndrome (FXS) is a multi-organ disease leading to mental retardation, macro-orchidism in males, and premature ovarian insufficiency in female carriers. FXS is also a prominent monogenic disease associated with autism spectrum disorders (ASD). FXS is typically caused by the loss of FRAGILE...

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Detalles Bibliográficos
Autores principales: Ascano, Manuel, Mukherjee, Neelanjan, Bandaru, Pradeep, Miller, Jason B., Nusbaum, Jeff, Corcoran, David L., Langlois, Christine, Munschauer, Mathias, Dewell, Scott, Hafner, Markus, Williams, Zev, Ohler, Uwe, Tuschl, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3528815/
https://www.ncbi.nlm.nih.gov/pubmed/23235829
http://dx.doi.org/10.1038/nature11737

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