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Oxidative stress contributes to outcome severity in a Drosophila melanogaster model of classic galactosemia
Classic galactosemia is a genetic disorder that results from profound loss of galactose-1P-uridylyltransferase (GALT). Affected infants experience a rapid escalation of potentially lethal acute symptoms following exposure to milk. Dietary restriction of galactose prevents or resolves the acute seque...
Autores principales: | Jumbo-Lucioni, Patricia P., Hopson, Marquise L., Hang, Darwin, Liang, Yongliang, Jones, Dean P., Fridovich-Keil, Judith L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529341/ https://www.ncbi.nlm.nih.gov/pubmed/22773758 http://dx.doi.org/10.1242/dmm.010207 |
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