A yeast model for amyloid-β aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity

Alzheimer’s disease is the most common neurodegenerative disease, associated with aggregation of amyloid-β (Aβ) peptides. The exact mechanism of neuronal cell dysfunction in Alzheimer’s disease is poorly understood and numerous models have been used to decipher the mechanisms leading to cellular dea...

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Detalles Bibliográficos
Autores principales: D’Angelo, Fabien, Vignaud, Hélène, Di Martino, Julie, Salin, Bénédicte, Devin, Anne, Cullin, Christophe, Marchal, Christelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529352/
https://www.ncbi.nlm.nih.gov/pubmed/22888099
http://dx.doi.org/10.1242/dmm.010108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529352/
https://www.ncbi.nlm.nih.gov/pubmed/22888099
http://dx.doi.org/10.1242/dmm.010108

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